Human CD243 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Human CD243 |
| Clone | [UIC2] |
| Host Species | Mouse |
| Reactive Species | primate |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.2 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Immunohistology Frozen, Flow cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistology Paraffin* |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse anti Human CD243, clone UIC2 recognizes an extracellular conformational epitope of CD243, also known as MDR1 (multi-drug resistance protein 1) and Pgp (P-glycoprotein), a multi pass transmembrane protein and member of the ABC transporter (ATP-binding cassette) family, containing two ABC transporter type 1 domains and two ABC transporter domains. CD243 acts as an active efflux pump for a diverse range of lipophillic compounds. CD243 is expressed at low levels in the cell membrane of peripheral blood leucocytes, and constitutively expressed on the apical plasma membrane of excretory epithelial cells of the kidney, liver, brain and small intestine. CD243 mediates resistance to many chemotherapeutic agents used for tumour suppression and |
| Immunogen | n/a |
| Other Names | [multidrug resistance protein 1; Multidrug resistance protein 1; multidrug resistance protein 1; P-glycoprotein 1; colchicin sensitivity; doxorubicin resistance; ATP-binding cassette, sub-family B (MDR/TAP), member 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD_antigen: CD243], [ABCB1; ABCB1; CLCS; MDR1; P-GP; PGY1; ABC20; CD243; GP170; MDR1; PGY1] |
| Gene, Accession # | [CD243], Gene ID: 5243, NCBI: NP_000918.2, UniProt: P08183 |
| Catalog # | MBS217348 |
| Price | $430 |
| Order / More Info | Human CD243 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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