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Antigenic Specificity | GRIN2D |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GRIN2D antibody detects endogenous levels of total GRIN2D. Function: Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg2+ (PubMed:9489750, PubMed:27616483, PubMed:26875626, PubMed:28126851). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:9489750).Subunit Structure: Heterotetramer. Forms heterotetrameric channels composed of two zeta subunits (GRIN1), and two epsilon |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane. Cell Junction > Synapse > Postsynaptic Cell Membrane. Predicted Cross Reactivity: Pig, Bovine, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Rabbit (100%), Dog (100%) |
Other Names | [EB11; estrogen receptor binding CpG island; GluN2D; Glutamate [NMDA] receptor subunit epsilon 4; Glutamate [NMDA] receptor subunit epsilon-4; Glutamate receptor ionotropic; glutamate receptor ionotropic NMDA 2D; Glutamate receptor, ionotropic, N-methyl D-aspartate 2D; Grin2d; N methyl D aspartate receptor subtype 2D; N methyl d aspartate receptor subunit 2D; N-methyl D-aspartate receptor subtype 2D; NMDA 2D; NMDAR2D; NMDE4; NMDE4_HUMAN; NR2D] |
Gene, Accession # | [GRIN2D], Gene ID: 2906, NCBI: NP_000827.2, UniProt: O15399 |
Catalog # | MBS9605541 |
Price | $240, $280 |
Order / More Info | GRIN2D Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |