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Antigenic Specificity | Mouse Prr5 (C-term), 277-305 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Prr5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the C-terminal region of mouse Prr5. Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-30 |
Immunogen | n/a |
Other Names | [Proline-rich protein 5; Protein observed with Rictor-1; Protor-1; Prr5 {ECO:0000250|UniProtKB:P85299}; Protor1] |
Gene, Accession # | [Prr5], Gene ID: 109270, NCBI: NP_666173.4, UniProt: Q812A5 |
Catalog # | MBS9202655 |
Price | $165, $370 |
Order / More Info | Mouse Prr5 (C-term), 277-305 Antibody from MYBIOSOURCE INC. |
Product Specific References | Johnstone, C.N., et al. Genomics 85(3):338-351(2005) Shan, Z., et al. Gene 303, 55-61 (2003) : |