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Antigenic Specificity | Phospho-eIF4E (Thr210) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-eIF4E (Thr210) Antibody detects endogenous levels of eIF4E only when phosphorylated at Thr210. Description: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.Post Translational Modifications: Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the eIF4F complex.Subunit Structure: eIF4F is a multi-subunit complex, the |
Immunogen | Immunogen: A synthesized peptide derived from human eIF4E around the phosphorylation site of Thr210. |
Other Names | [AUTS19; CBP; eIF 4E; eIF 4F 25 kDa subunit; EIF 4F; eIF-4E; eIF-4F 25 kDa subunit; eIF4E; EIF4E1; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4 E; Eukaryotic translation initiation factor 4E; Eukaryotic translation initiation factor 4E like 1; IF4E_HUMAN; Messanger RNA Cap Binding Protein eIF 4E; MGC111573; mRNA cap binding protein; mRNA cap-binding protein] |
Gene, Accession # | [eIF4E], Gene ID: 1977, NCBI: NP_001124150.1, UniProt: P06730 |
Catalog # | MBS9610564 |
Price | $225, $280, $340 |
Order / More Info | Phospho-eIF4E (Thr210) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |