Phospho-eIF4E (Thr210) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-eIF4E (Thr210)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, ratpredicted: porcine, bovine, horse, sheep, rabbit, dog, chicken, Xenopus
Isotypen/a
Formatpeptide affinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA)
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DescriptionSpecificity: Phospho-eIF4E (Thr210) Antibody detects endogenous levels of eIF4E only when phosphorylated at Thr210. Description: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.Post Translational Modifications: Phosphorylation increases the ability of the protein to bind to mRNA caps and to form the eIF4F complex.Subunit Structure: eIF4F is a multi-subunit complex, the
ImmunogenImmunogen: A synthesized peptide derived from human eIF4E around the phosphorylation site of Thr210.
Other Names[AUTS19; CBP; eIF 4E; eIF 4F 25 kDa subunit; EIF 4F; eIF-4E; eIF-4F 25 kDa subunit; eIF4E; EIF4E1; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4 E; Eukaryotic translation initiation factor 4E; Eukaryotic translation initiation factor 4E like 1; IF4E_HUMAN; Messanger RNA Cap Binding Protein eIF 4E; MGC111573; mRNA cap binding protein; mRNA cap-binding protein]
Gene, Accession #[eIF4E], Gene ID: 1977, NCBI: NP_001124150.1, UniProt: P06730
Catalog #MBS9610564
Price$225, $280, $340
Order / More InfoPhospho-eIF4E (Thr210) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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