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Antigenic Specificity | GLP1R |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GLP1R (glucagon like peptide 1 receptor) encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in GLP1R are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of GLP1R results in multiple transcript variants. |
Immunogen | Immunogen: Synthetic Peptide |
Other Names | [Rabbit GLP1R; GLP1R; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R] |
Gene, Accession # | [GLP1R], Gene ID: 2740, NCBI: NP_002053.3, UniProt: P43220 |
Catalog # | MBS9707945 |
Price | $130, $220, $325 |
Order / More Info | GLP1R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |