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Antigenic Specificity | Human E3 SUMO-protein ligase PIAS3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation. |
Immunogen | Immunogen: Recombinant human E3 SUMO-protein ligase PIAS3 protein (399-628aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-8154 / sc-14017 |
Other Names | [Protein inhibitor of activated STAT protein 3; PIAS3], [PIAS3; PIAS3; ZMIZ5] |
Gene, Accession # | [PIAS3], Gene ID: 10401, NCBI: NP_006090.2, UniProt: Q9Y6X2 |
Catalog # | MBS969099 |
Price | $120, $160 |
Order / More Info | Human E3 SUMO-protein ligase PIAS3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |