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Antigenic Specificity | Daxx |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, rat, human. predicted: mouse |
Isotype | n/a |
Format | serum |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Daxx (death-domain-associated protein) was originally identified as a cytoplasmic protein that binds to the death domain of the transmembrane death receptor Fas. It is now that known that the a large porportion of Daxx molecules are nuclear and associate with the promyelocytic leukaemia nuclear body (PML-NB) and other subnuclear domains.Daxx is ubiquitously expressed, and particularly high levels of Daxx have been reported in the thymus and testes. At the cellular level Daxx may be found in cytoplasm and within heterochromatic regions of the nucleus. Daxx has been reported to interact and co-localize with Pml in the nucleus of tumor cell lines and primary cells. Daxx is thought to have both pro- and anti-apoptotic functions depending on the |
Immunogen | Immunogen Information: A synthetic peptide of Daxx protein (amino acids 272-291 ERLINKPGPDTFPDYGDVLR) was used as immunogen for this antibody |
Other Names | [DAXX; BING2; DAP6; Daxx; EAP1; ETS1-associated protein 1; Fas death domain-associated protein; to Daxx; Daxx; Daxx], [DAXX; DAXX; DAP6; EAP1; BING2; BING2; DAP6; hDaxx; EAP1] |
Gene, Accession # | [DAXX], Gene ID: 1616, NCBI: Q9UER7.2, UniProt: Q9UER7 |
Catalog # | MBS668616 |
Price | $270 |
Order / More Info | Daxx Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |