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Antigenic Specificity | Progesterone Receptor (Phospho-Ser190) |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunoblotting (IB), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous human progesterone receptor only when phosphorylated at serine 190. Progesterone receptor (PR) is a nuclear hormone receptor of the NR3C class which includes mineralocorticoid, glucocorticoid, and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins which are shed upon activation. Progesterone receptors signal directly via DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins with transcription factors such as NF-kappa B, AP-1, or STAT. Progesterone receptor expression is induced by estrogen, and the human gene encoding the progesterone receptor has been localized to 11q22. |
Immunogen | Antigen: Peptide sequence that includes phosphorylation site of serine 190 (G-L-S(p)-P-A) derived from human progesterone receptor and conjugated to KLH. |
Other Names | [progesterone receptor isoform B; Progesterone receptor; progesterone receptor; progesterone receptor; Nuclear receptor subfamily 3 group C member 3], [PGR; PGR; PR; NR3C3; NR3C3; PR] |
Gene, Accession # | Gene ID: 5241, NCBI: NP_000917.3, UniProt: P06401 |
Catalog # | MBS191085 |
Price | $340 |
Order / More Info | Progesterone Receptor (Phospho-Ser190) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |