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Antigenic Specificity | NSE gamma (Neuron Specific Enolase, gamma) (Neuroendocrine Marker) |
Clone | [ENO2/1375] |
Host Species | Mouse |
Reactive Species | human, mouse, rat. |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas. It it be usually employed in combination with other markers such as Synaptophysin, Chromogranin A, and Neurofilament. |
Immunogen | Immunogen: A synthetic peptide corresponding to aa416-433 of human NSE gamma. Cellular Localization: Cytoplasmic |
Other Names | [2-phospho-D-glycerate hydrolyase; ENO2; ENOG; Enolase 2 gamma neuronal; Enolase2; Gamma-enolase; Neural enolase; Neuron specific gamma enolase; Neuron-specific enolase; NSE], [ENO2] |
Gene, Accession # | [NSE gamma], Gene ID: 2026, NCBI: NP_001966.1, UniProt: P09104 |
Catalog # | MBS439932 |
Price | $190, $340, $340 |
Order / More Info | NSE gamma (Neuron Specific Enolase, gamma) (Neuroendocrine Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Verma, M., et al. 1994. DNA sequences encoding enolase are remarkably conserved from yeast to mammals. Life Sci. 55: 893-899. |