SAP102 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySAP102
Clone[S19-2]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
FormatATTO 565 conjugate
Size0.1 mg
Concentration1mg/mL
ApplicationsWestern (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
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DescriptionBackground Info: Detects ~105kDa. No cross-reactivity against PSD95, SAP97 or Chapsyn-110. Scientific Background: Synapse-associated protein 102 belongs to the membrane-associated guanylate kinase protein family and is a homolog of the Drosophila dis large tumor suppressor protein. SAP102 has extensive sequence homology to the PSD 95 family of proteins that facilitate ion channel clustering at synaptic terminal (1, 2). SAP102 consists of three 90 amino acids PDZ domains at its amino terminus, a Src homology 3 domain and a guanylate kinase domain (3). All three PDZ domains of SAP102 participate in binding to the NMDA reception, interacting specifically with the carboxy-terminal domain of the N-methyl-D-aspartate receptor 2B (NR2B). The inter
Immunogenn/a
Other Names[DLG3; MRX90; NEDLG; XLMR; Disks large homolog 3; PSD-95/SAP90-related protein 1; Synapse-associated protein 102; SAP-102], [Dlg3; Dlg3; Dlgh3; Dlgh3; SAP-102; SAP102]
Gene, Accession #Gene ID: 58948, NCBI: NP_113827.1, UniProt: Q62936
Catalog #MBS800043
Price$375
Order / More InfoSAP102 Antibody from MYBIOSOURCE INC.
Product Specific References1. Muller B.M., et al. (1996) Neuron 17: 255-265. 2. Lau L. F., et al. (1996) J. Biol. Chem. 271: 21622-21628. 3. Cuthbert P.C., et al. (2007) J Neuroscience 27:2673-2682. 4. Lau L.F., et al. (1996) J Biol Chem 274:5782-5790.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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