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Antigenic Specificity | PTAFR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-snglycero- 3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, a |
Immunogen | Immunogen: Synthetic peptide of human PTAFR |
Other Names | [PAFR] |
Gene, Accession # | [PTAFR], Gene ID: 5724, NCBI: NP_000943, UniProt: P25105 |
Catalog # | MBS2516831 |
Price | $110, $150, $225 |
Order / More Info | PTAFR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |