Edit |   |
---|---|
Antigenic Specificity | AMPK beta 1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-termi |
Immunogen | Immunogen: A synthesized peptide derived from human AMPK beta 1 |
Other Names | [5'-AMP-activated protein kinase subunit beta-1; AMPK subunit beta-1; AMPKb; PRKAB1; AMPK], [PRKAB1] |
Gene, Accession # | [AMPK beta 1], Gene ID: 5564, NCBI: NP_006244.2, UniProt: Q9Y478 |
Catalog # | MBS179983 |
Price | $160, $340, $340 |
Order / More Info | AMPK beta 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |