SIGLEC8 (N-term), 94-122 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySIGLEC8 (N-term), 94-122
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis SIGLEC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the N-terminal region of human SIGLEC8. Sialic acid-binding immunoglobulin (Ig)-like lectins, orSIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1transmembrane proteins each having a unique expression pattern,mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-likesubgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptortyrosine-based inhibitory motif, or ITIM (see MIM 604964), and amotif homologous to one identified in signaling lymphocyteactivation molecule (SLAM; MIM 603492) that mediates an
Immunogenn/a
Other Names[Sialic acid-binding Ig-like lectin 8; Siglec-8; Sialoadhesin family member 2; SAF-2; SIGLEC8; SAF2]
Gene, Accession #[SIGLEC8], Gene ID: 27181, NCBI: NP_055257.2, UniProt: Q9NYZ4
Catalog #MBS9214391
Price$165, $370
Order / More InfoSIGLEC8 (N-term), 94-122 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGao, P.S., et al. Eur. J. Hum. Genet. 18(6):713-719(2010) Davila, S., et al. Genes Immun. 11(3):232-238(2010) Hudson, S.A., et al. J. Pharmacol. Exp. Ther. 330(2):608-612(2009) Bochner, B.S. Clin. Exp. Allergy 39(3):317-324(2009) von Gunten, S., et al. Autoimmun Rev 7(6):453-456(2008)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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