PH domain leucine-rich repeat-containing protein phosphatase 2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PH domain leucine-rich repeat-containing protein phosphatase 2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC), Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PHLPP2 is a protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser-657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor. |
| Immunogen | Immunogen: Synthetic peptide derived from the human PHLPP2 protein |
| Other Names | [PHLPP2; PH domain leucine-rich repeat-containing protein phosphatase 2; PH domain leucine-rich repeat-containing protein phosphatase-like; PHLPP-like], [PHLPP2; PHLPP2; PHLPPL; KIAA0931; PHLPPL; PHLPP-like] |
| Gene, Accession # | Gene ID: 23035, NCBI: NP_055835.2, UniProt: Q6ZVD8 |
| Catalog # | MBS395715 |
| Price | $340 |
| Order / More Info | PH domain leucine-rich repeat-containing protein phosphatase 2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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