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Antigenic Specificity | c-Src (Tyr-215), phospho-specific [Conserved site] |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was cross-adsorbed to phospho-tyrosine coupled to agarose then affinity purified using phospho-c-Src (Tyr-215) peptide (without carrier). The antibody detects a 60 kDa* protein on SDS-PAGE immunoblots of mouse SYF cells transformed with c-Src and human A431 cells that have been treated with pervanadate. c-Src was the first proto-oncogenic non-receptor tyrosine kinase characterized in human. The Src family is composed of nine members in vertebrates, including c-Src, Yes, Fgr, Yrk, Fyn, Lyn, Hck, Lck, and Blk. Src-family kinases transduce signals that are involved in the control of avariety of cellular processes, including proliferation, differentiation, motility, and adhesion. Src-family kinases contain an N-terminal cell memb |
Immunogen | Immunogen: c-Src (Tyr-215) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 215 of human c-Src. This sequence has homology to the conserved site in other Src family members, such as hck, fyn, csk, and yes. |
Other Names | [c-Src (Tyr-215); phospho-specific; Src], [SRC; SRC; ASV; SRC1; c-SRC; p60-Src; SRC1] |
Gene, Accession # | Gene ID: 6714, UniProt: P12931 |
Catalog # | MBS472018 |
Price | $385 |
Order / More Info | c-Src (Tyr-215), phospho-specific [Conserved site] Antibody from MYBIOSOURCE INC. |
Product Specific References | • Stover, D.R. et al. (1996) J Biol Chem 271(21):12481.• Vadlamudi, R.K. et al. (2003) FEBS Letters 543:76. |