Human Pregnancy-specific-protein (PSG) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Pregnancy-specific-protein (PSG)
Clone[BAP3]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunohistochemistry(IHC)
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DescriptionSpecificity: anti-human PSG (CD 66f); epitope in the B2 domain (present in most PSG). Background: The human pregnancy-specific glycoprotein family (PSG) is a group of closely related secreted glycoproteins which are highly expressed in placental syncytiotrophoblast cells of fetal origin (1). PSG are commonly expressed in tumors of trophoblast origin (hydatidiform mole, choriocarcinoma). They represent the most abundant fetal protein in the maternal blood at term. Together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes, the human PSG genes form the CEACAM gene family (2). PSG stimulate secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17 (3).
ImmunogenImmunogen: Immunogen: extracted protein of human PSG
Other Names[pregnancy-specific glycoprotein 1; CD66f], [PSG1; PSG1; SP1; B1G1; PBG1; CD66f; PSBG1; PSG95; PSGGA; DHFRP2; PSBG-1; PSGIIA; FL-NCA-1/2; PS-beta-C/D; PS-beta-G-1; B1G1; PSBG1; PSGGA; PS-beta-G-1; PSBG-1; Pregnancy-specific glycoprotein 1; FL-NCA-1/2; PS-beta-C/D]
Gene, Accession #Gene ID: 5669, NCBI: NP_001171754.1, UniProt: P11464
Catalog #MBS468004
Price$505
Order / More InfoHuman Pregnancy-specific-protein (PSG) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBeauchemin N, Draber P, Dveksler G, Gold P, Gray-Owen S, Grunert F, Hammarstrom S, Holmes KV,Karlsson A, Kuroki M, Lin SH, Lucka L, Najjar SM, Neumaier M, Obrink B, Shively JE, Skubitz KM,Stanners CP, Thomas P, Thompson JA, Virji M, von Kleist S, Wagener C, Watt S and Zimmermann W(1999). Redefined nomenclature for members of the carcinoembryonic antigen family. Exp Cell Res 252:243-249.Hammarstrom S (1999). The carcinoembryonic antigen (CEA) family: structures, suggested functions andexpression in normal and malignant tissues. Semin Cancer Biol 9: 67-81.Snyder SK, Wessner DH, Wessells JL, Waterhouse RM, Wahl LM, Zimmermann W and Dveksler GS(2001). Pregnancy-specific glycoproteins function as immunomodulators by inducing secretion of IL-10, IL-6and TGF-beta1 by human monocytes. Am J Reprod Immunol 45: 205-216.Sokolov AV, Kozliaeva GA, Mesniankina NV and Tatarinov I (1978). [Isolation and purification of specificbeta1-G-globulin]. Vopr Med Khim 24: 240-244.Zhou GQ, Baranov V, Zimmermann W, Grunert F, Erhard B, Mincheva-Nilsson L, Hammarstrom Sand Thompson J (1997). Highly specific monoclonal antibody demonstrates that pregnancy- specificglycoprotein (PSG) is limited to syncytiotrophoblast in human early and term placenta. Placenta 18: 491-501.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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