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Antigenic Specificity | KDM1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4 (By similarity). |
Immunogen | Immunogen: Recombinant human Lysine-specific histone demethylase 1B protein |
Other Names | [Lysine-specific histone demethylase 1B; Flavin-containing amine oxidase domain-containing protein 1; Lysine-specific histone demethylase 2; KDM1B; AOF1; C6orf193; LSD2] |
Gene, Accession # | [KDM1B], Gene ID: 221656, NCBI: NP_694587.3, UniProt: Q8NB78 |
Catalog # | MBS7043981 |
Price | $160, $235 |
Order / More Info | KDM1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |