LIN28 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LIN28 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG2a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody detects endogenous levels of LIN28, and does not cross-react with related proteins. Acts as a ?translational enhancer?, driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression (By similarity). Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Act |
| Immunogen | Immunogen: Purified recombinant human LIN28 protein fragments expressed in E Coli. Cellular Localization: Cytoplasm; Nucleus |
| Other Names | [AL024421; CSDD1; FLJ12457; Lin 28; Lin 28 homolog A; Lin-28; Lin-28 homolog (C. elegans); Lin-28A; Lin28; Lin28a; Protein lin-28 homolog A; RNA binding protein lin 28; Tex17; ZCCHC1; Zinc finger CCHC domain containing 1; Zinc finger CCHC domain-containing protein 1], [CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A] |
| Gene, Accession # | [LIN28], Gene ID: 79727, NCBI: NP_078950.1, UniProt: Q9H9Z2 |
| Catalog # | MBS857854 |
| Price | $300 |
| Order / More Info | LIN28 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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