STAT3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | STAT3 |
| Clone | [1200CT146.104.153] |
| Host Species | Mouse |
| Reactive Species | human (predicted reactivity: mouse, porcine, rat) |
| Isotype | IgG2a,kappa |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This STAT3 antibody is generated from a mouse immunized with a recombinant protein from human. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity). |
| Immunogen | n/a |
| Other Names | [Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF] |
| Gene, Accession # | [STAT3], Gene ID: 6774, NCBI: NP_003141.2, UniProt: P40763 |
| Catalog # | MBS9200077 |
| Price | $165, $370 |
| Order / More Info | STAT3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Akira S.,et al.Cell 77:63-71(1994). Della Pietra L.,et al.Gene 213:119-124(1998). Ota T.,et al.Nat. Genet. 36:40-45(2004). Della Pietra L.,et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases. Zhang X.,et al.Science 267:1990-1994(1995). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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