VAV3 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-VAV3 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | VAV3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Exchange factor for GTP-binding proteins RhoA, RhoG and, to a lesser extent, Rac1. Binds physically to the nucleotide-free states of those GTPases. Plays an important role in angiogenesis. Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. May be important for integrin-mediated signaling, at least in some cell types. In osteoclasts, along with SYK tyrosine kinase, required for signaling through integrin alpha-v/beta-1 (ITAGV-ITGB1), a crucial event for osteoclast proper cytoskeleton organization and function. This signaling pathway involves RAC1, but not RHO, activation. Necessary for proper wound healing. In the course of wound healing, required |
| Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 560-680 of human VAV3 (NP 006104.4). |
| Other Names | [guanine nucleotide exchange factor VAV3 isoform 2; Guanine nucleotide exchange factor VAV3; guanine nucleotide exchange factor VAV3; vav guanine nucleotide exchange factor 3] |
| Gene, Accession # | [VAV3], Gene ID: 10451, NCBI: NP_001073343.1, UniProt: Q9UKW4 |
| Catalog # | MBS8549886 |
| Price | $280 |
| Order / More Info | VAV3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies