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Antigenic Specificity | VARP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The VPS9 ankyrin repeat protein (VARP) binds to the Rab21, a guanine nucleotide exchange factor that plays an essential role in endocytic trafficking. VARP localizes to early endosomes and is thought to regulate endosome dynamics. VARP also interacts with TI-VAMP/VAMP7, a vesicular SNARE that mediates an exocytic pathway that is crucial to neurite growth. Depletion of VARP by RNA interference impairs neurite growth, suggesting that VARP is a positive regulator of neurite growth. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide near the center of human VARP. |
Other Names | [VPS9 ankyrin repeat protein, Ankyrin repeat domain-containing protein 27, ANKRD27, PP12899] |
Gene, Accession # | [VARP], Gene ID: 84079, NCBI: NP_115515 |
Catalog # | MBS9408977 |
Price | $320 |
Order / More Info | VARP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |