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Antigenic Specificity | TR10A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total TR10A protein. Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.Pan G., Science 276:111-113(1997).The MGC Project Team, Genome Res. 14:2121-2127(2004).Chaudhary P.M., Immunity 7:821-830(1997). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human TR10A. |
Other Names | [Tumor necrosis factor receptor superfamily member 10A [Precursor]; Death receptor 4; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1] |
Gene, Accession # | [TR10A], Gene ID: 8797, NCBI: NP_003835.3, UniProt: O00220 |
Catalog # | MBS9411239 |
Price | $200, $255 |
Order / More Info | TR10A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |