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Antigenic Specificity | ASK1 (MEKK5/MAP3K5) (S1033) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human; predicted reactivity: mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ASK1(MEKK5/MAP3K5) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1011-1040 amino acids from human ASK1(MEKK5/MAP3K5). Description: Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantl |
Immunogen | n/a |
Other Names | [Mitogen-activated protein kinase kinase kinase 5; Apoptosis signal-regulating kinase 1; ASK-1; MAPK/ERK kinase kinase 5; MEK kinase 5; MEKK 5; MAP3K5; ASK1; MAPKKK5; MEKK5] |
Gene, Accession # | [MAP3K5], Gene ID: 4217, NCBI: NP_005914.1, UniProt: Q99683 |
Catalog # | MBS9217158 |
Price | $165, $370 |
Order / More Info | ASK1 (MEKK5/MAP3K5) (S1033) Antibody from MYBIOSOURCE INC. |
Product Specific References | Min,W.,Circ. Res. 102 (7), 840-848 (2008). Li,X.,Cell Death Differ. 15 (4), 739-750 (2008). Noguchi,T.,J. Biol. Chem. 283 (12), 7657-7665 (2008). |