Edit |   |
---|---|
Antigenic Specificity | Caspase 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 200 ug/ml |
Applications | Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-1 is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1 beta and IL-18 into active cytokines. Like other caspases, Caspase-1 itself is synthesized as a pro-enzyme that is cleaved during activation into a large and small subunits. The cellular role of caspase-1 appears limited to cytokine activation as they do not have obvious roles in apoptosis. |
Immunogen | Immunogen: Caspase 1 antibody was raised in Rabbit using synthetic peptide surrounding amino acid 132 of human caspase-1 as the immunogen. |
Other Names | [Rabbit Caspase 1; Caspase 1; Caspase 1; Interleukin-1 beta convertase; IL1B-convertase; Caspase -1; Caspase 1; ICE; Caspase 1; Caspase -1; p45; Caspase 1; IL1BC; IL1BCE; CASP-1; CASP1; IL-1BC; P45] |
Gene, Accession # | [CASP-1], Gene ID: 25166 |
Catalog # | MBS5311125 |
Price | $560 |
Order / More Info | Caspase 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |