PLAU Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PLAU |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: PLAU antibody detects endogenous levels of total PLAU. Description: The human urokinase-type plasminogen activator receptor (uPAR) is a 55-65 kDa, highly glycosylated, GPI-anchored cell surface receptor (the deglycosylated protein is 35 kDa) (1-3). It is a central player in the plasminogen activation pathway. uPAR binds with high affinity to a serine protease urokinase-type plasminogen activator (uPA) and converts plasminogen to its active form plasmin in a spatially restricted manner on the cell surface (4). Plasmin further carries out the activation of uPA, which is inhibited by serpins, such as plasminogen activator inhibitors (5). Therefore, uPAR plays a key role in regulating extracellular proteolysis. In addition, uPAR pl |
| Immunogen | Immunogen: A synthesized peptide derived from human PLAU Subcellular Location: Secreted. Tissue Specificity: Expressed in the prostate gland and prostate cancers. Predicted Cross Reactivity: Horse, Rabbit Similarity: Horse (82%), Rabbit (82%) |
| Other Names | [ATF; ATF uPA; BDPLT5; Plasminogen activator; Plasminogen activator urinary; Plasminogen activator urokinase; PLAU; QPD; u PA; U plasminogen activator; u-PA; U-plasminogen activator; uPA; URK; UROK_HUMAN; Urokinase plasminogen activator; Urokinase type plasminogen activator; Urokinase type plasminogen activator precursor; Urokinase-type plasminogen activator chain B] |
| Gene, Accession # | [PLAU], Gene ID: 5328, NCBI: NP_001138503.1, UniProt: P00749 |
| Catalog # | MBS9607557 |
| Price | $240, $280 |
| Order / More Info | PLAU Antibody from MYBIOSOURCE INC. |
| Product Specific References | Liu Y, Zheng J, Zhang Y, Wang Z, Yang Y, Bai M, Dai Y; Journal: Neurochem Res. Fucoxanthin Activates Apoptosis via Inhibition of PI3K/Akt/mTOR Pathway and Suppresses Invasion and Migration by Restriction of p38-MMP-2/9 Pathway in Human Glioblastoma Cells. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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