Nav beta2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Nav beta2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Nav beta2 |
| Clone | [S395-68] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2B |
| Format | APC-Cy7 conjugate |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~40 kDa. Does not cross-reat with NavBeta1, Navbeta3, or Navbeta4. NavBeta2 or Scn2B, plays a crucial role in the assembly, expression and functional modulation of the heterotrimeric complex of the sodium channel. The subunit, beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. It also interacts with TNR, playing a crucial role in clustering and regulation of activity of sodium channels at the nodes of Ranvier (1, 2). Mutations in this gene have been linked to Brugada syndrome and atrial fibrillation (3). |
| Immunogen | Immunogen: Fusion protein amino acids 1-215 (full-length) of mouse Nav beta2 |
| Other Names | [Mouse Mouse Nav beta2 IgG2B; Nav beta2 : APC/Cy7; Sodium channel subunit beta-2; Scn2b; UNQ326/PRO386; Gm183] |
| Gene, Accession # | [Nav beta2], Gene ID: 72821, NCBI: NP_001014761.1, UniProt: Q56A07 |
| Catalog # | MBS8003592 |
| Price | $510 |
| Order / More Info | Nav beta2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Genes and mapped phenotypes. (n.d.). Retrieved March 16, 2015. 2. Eubanks J., Srinivasan J., Dinulos M.B., Disteche C.M., Catterall W.A. (1997) Neuroreport. 8(12): 2775-2779. 3. Riuro H., et al. (2013) Hum Mutat. 34(7): 961-966. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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