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Antigenic Specificity | Human IL-1 R2 |
Clone | [4T28] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) - Formalin, Neutralization |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Two distinct types of receptors that bind the pleiotropic cytokines IL-1 alpha and IL-1 beta have been described. The IL-1 receptor Type I is an 80 kDa transmembrane protein that is expressed predominantly by T cells, fibroblasts, and endothelial cells. IL-1 receptor Type II is a 68 kDa transmembrane protein found on B lymphocytes, neutrophils, monocytes, large granular leukocytes and, endothelial cells. Both receptors are members of the immunoglobulin superfamily and show approximately 28% sequence similarity in their extracellular domains. The two receptor types do not heterodimerize in a receptor complex. IL-1 RII has a short cytoplasmic domain and does not transduce IL-1 signals. In addition to the membrane-bound form of IL-1 RII, a nat |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-1 R II extracellular domain. Antigen: Recombinant human IL1-R II EC domain. |
Other Names | [Il1r2; CD121b; Il1r-2; Interleukin 1 receptor 2], [IL1R2; IL1R2; IL1RB; CD121b; IL1R2c; CDw121b; IL-1R-2; IL-1RT2; IL-1RT-2; IL1RB; IL-1R-2; IL-1RT-2; IL-1RT2; IL-1R-beta; mIL-1R2; mIL-1RII; sIL-1R2; sIL-1RII] |
Gene, Accession # | [IL-1 R2], Gene ID: 7850, NCBI: NP_001248348.1, UniProt: P27930 |
Catalog # | MBS690482 |
Price | $490 |
Order / More Info | Human IL-1 R2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |