Human IL-1 R2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman IL-1 R2
Clone[4T28]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) - Formalin, Neutralization
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DescriptionTwo distinct types of receptors that bind the pleiotropic cytokines IL-1 alpha and IL-1 beta have been described. The IL-1 receptor Type I is an 80 kDa transmembrane protein that is expressed predominantly by T cells, fibroblasts, and endothelial cells. IL-1 receptor Type II is a 68 kDa transmembrane protein found on B lymphocytes, neutrophils, monocytes, large granular leukocytes and, endothelial cells. Both receptors are members of the immunoglobulin superfamily and show approximately 28% sequence similarity in their extracellular domains. The two receptor types do not heterodimerize in a receptor complex. IL-1 RII has a short cytoplasmic domain and does not transduce IL-1 signals. In addition to the membrane-bound form of IL-1 RII, a nat
ImmunogenAntibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-1 R II extracellular domain. Antigen: Recombinant human IL1-R II EC domain.
Other Names[Il1r2; CD121b; Il1r-2; Interleukin 1 receptor 2], [IL1R2; IL1R2; IL1RB; CD121b; IL1R2c; CDw121b; IL-1R-2; IL-1RT2; IL-1RT-2; IL1RB; IL-1R-2; IL-1RT-2; IL-1RT2; IL-1R-beta; mIL-1R2; mIL-1RII; sIL-1R2; sIL-1RII]
Gene, Accession #[IL-1 R2], Gene ID: 7850, NCBI: NP_001248348.1, UniProt: P27930
Catalog #MBS690482
Price$490
Order / More InfoHuman IL-1 R2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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