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Antigenic Specificity | Human Serine/threonine-protein kinase PAK 4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, growth, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates LIMK1, a kinase that also inhibits the activity of cofilin. Phosphorylates integrin beta5/ITGB5 and thus re |
Immunogen | Immunogen: Recombinant human Serine/threonine-protein kinase PAK 4 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-18622 / sc-28779 |
Other Names | [p21-activated kinase 4; PAK-4; KIAA1142], [PAK4; PAK4; KIAA1142; PAK-4] |
Gene, Accession # | [PAK4], Gene ID: 10298, NCBI: NP_001014831.1, UniProt: O96013 |
Catalog # | MBS1492927 |
Price | $160, $235 |
Order / More Info | Human Serine/threonine-protein kinase PAK 4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |