DKK1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | DKK1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This DKK1 antibody is generated from a rabbit immunized with a recombinant protein of human DKK1. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. |
| Immunogen | n/a |
| Other Names | [Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK; DKK1] |
| Gene, Accession # | [DKK1], Gene ID: 22943, NCBI: NP_036374.1, UniProt: O94907 |
| Catalog # | MBS9203825 |
| Price | $165, $370 |
| Order / More Info | DKK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Fedi P.,et al.J. Biol. Chem. 274:19465-19472(1999). Krupnik V.E.,et al.Gene 238:301-313(1999). Tate G.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases. Roessler E.,et al.Cytogenet. Cell Genet. 89:220-224(2000). Clark H.F.,et al.Genome Res. 13:2265-2270(2003). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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