MUL1 (C-term), 272-301 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMUL1 (C-term), 272-301
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: monkey)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis MUL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human MUL1. E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Immunogenn/a
Other Names[Mitochondrial ubiquitin ligase activator of NFKB 1; 632-; E3 SUMO-protein ligase MUL1; E3 ubiquitin-protein ligase MUL1; Growth inhibition and death E3 ligase; Mitochondrial-anchored protein ligase; MAPL; Putative NF-kappa-B-activating protein 266; RING finger protein 218; MUL1; C1orf166; GIDE; MAPL; MULAN; RNF218]
Gene, Accession #[MUL1], Gene ID: 79594, NCBI: NP_078820.2, UniProt: Q969V5
Catalog #MBS9208122
Price$165, $370
Order / More InfoMUL1 (C-term), 272-301 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLaure, L., et al. FEBS J. 277(20):4322-4337(2010) Braschi, E., et al. EMBO Rep. 10(7):748-754(2009) Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009) Zhang, B., et al. Cell Res. 18(9):900-910(2008) Zhang, H., et al. Biochem. Biophys. Res. Commun. 366(4):898-904(2008)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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