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Antigenic Specificity | MUL1 (C-term), 272-301 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: monkey) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MUL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human MUL1. E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
Immunogen | n/a |
Other Names | [Mitochondrial ubiquitin ligase activator of NFKB 1; 632-; E3 SUMO-protein ligase MUL1; E3 ubiquitin-protein ligase MUL1; Growth inhibition and death E3 ligase; Mitochondrial-anchored protein ligase; MAPL; Putative NF-kappa-B-activating protein 266; RING finger protein 218; MUL1; C1orf166; GIDE; MAPL; MULAN; RNF218] |
Gene, Accession # | [MUL1], Gene ID: 79594, NCBI: NP_078820.2, UniProt: Q969V5 |
Catalog # | MBS9208122 |
Price | $165, $370 |
Order / More Info | MUL1 (C-term), 272-301 Antibody from MYBIOSOURCE INC. |
Product Specific References | Laure, L., et al. FEBS J. 277(20):4322-4337(2010) Braschi, E., et al. EMBO Rep. 10(7):748-754(2009) Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009) Zhang, B., et al. Cell Res. 18(9):900-910(2008) Zhang, H., et al. Biochem. Biophys. Res. Commun. 366(4):898-904(2008) |