CD61/Integrin beta-3/Platelet Glycoprotein IIIa (Platelet Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD61/Integrin beta-3/Platelet Glycoprotein IIIa (Platelet Marker)
Clone[Y2/51]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG1, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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DescriptionReacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the alphaV-chain (CD51) to form vitronectin receptor, or with the alphaIIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61). The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megaka
ImmunogenImmunogen: Phytohemagglutinin (PHA)-stimulated peripheral blood cells Cellular Localization: Cell Surface
Other Names[BDPLT2; GP3A; GPIIIa; GT; HPA 1; HPA 4; Integrin beta-3; ITGB3; NAIT; Platelet fibrinogen receptor beta subunit; Platelet glycoprotein IIIa; PTP]
Gene, Accession #[CD61], Gene ID: 3690, NCBI: NP_000203.2, UniProt: P05106
Catalog #MBS4380052
Price$190, $340, $340
Order / More InfoCD61/Integrin beta-3/Platelet Glycoprotein IIIa (Platelet Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGatter KC, Cordell JL, Turley H, Heryet A, Kieffer N, Anstee DJ, et al. The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens. Histopathology 1988; 13:257 -67.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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