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Antigenic Specificity | SHB - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, human, mouse, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against SHB. It was validated on Western Blot using a cell lysate as a positive control.Target Description: SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SHB |
Other Names | [SH2 domain-containing adapter protein B; SH2 domain-containing adapter protein B; SH2 domain-containing adapter protein B; SH2 domain containing adaptor protein B] |
Gene, Accession # | [SHB], Gene ID: 6461, NCBI: NP_003019, UniProt: Q15464 |
Catalog # | MBS3214042 |
Price | $335 |
Order / More Info | SHB - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |