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Antigenic Specificity | Neurofilament alpha-internexin/NF66 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | serum |
Size | 0.1 mL |
Concentration | n/a |
Applications | Immunofluorescence (IF), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | alpha-internexin is a ~66 kDa Class IV intermediate filament originally discovered as it copurifies with other neurofilament subunits. It is related to but distinct from the better known neurofilament triplet proteins, NF-L, NF-M and NF-H, having similar protein sequence motifs and a similar intron organization. It is expressed in large amounts early in neuronal development, but is downregulated in many neurons as development procedes. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M anbd NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and |
Immunogen | Immunogen: recombinant alpha-internexin |
Other Names | n/a |
Gene, Accession # | [NF66] |
Catalog # | MBS555198 |
Price | $380 |
Order / More Info | Neurofilament alpha-internexin/NF66 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |