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Antigenic Specificity | MD-2 [9F1B1] |
Clone | [9F1B1] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MD-2 Monoclonal Antibody: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4. |
Immunogen | Immunogen: Mouse monoclonal MD-2 antibody was raised against a recombinant protein corresponding to amino acids 2 to 160 of human MD-2. Buffer: MD-2 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [MD-2 [9F1B1] : MD2; MD-2; ly-96; ESOP-1; lymphocyte antigen 96], [LY96; LY96; MD2; MD-2; ly-96; ESOP-1; ESOP1; MD2; Ly-96] |
Gene, Accession # | [LY96], Gene ID: 23643, NCBI: NP_056179, UniProt: Q9Y6Y9 |
Catalog # | MBS150024 |
Price | $375 |
Order / More Info | MD-2 [9F1B1] Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |