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Antigenic Specificity | MAPKAP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MAPKAP1 Antibody: MAPKAP1 was initially identified as the human homolog of S. pombe SIN1. Recent evidence has shown that it identical to Mip1, a protein that interacts with MEKK2, a member of the mitogen-activated protein kinase (MAPK) intracellular signaling network. MAPKAP1 is thought to prevent MEKK2 activation and dimerization by forming a complex with the inactive and non-phosphorylated MEKK2, thereby blocking the JNK1/2, ERK1/2, p38 and ERK5 MAPKs. MAPKAP1 has also been shown to play a role in the TOR signaling process, a pathway that is involved in controlling cell growth and proliferation in response to environmental cues such as nutrients, growth factors and hormones. Experiments showed that MAPKAP1 helped to maintain the TOR/ricto |
Immunogen | Immunogen: MAPKAP1 antibody was raised against a 18 amino acid synthetic peptide from near the center of human MAPKAP1. Buffer: MAPKAP1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [MAPKAP1; MIP1; SIN1; JC310; SIN1b; SIN1g; MIP1; Target of rapamycin complex 2 subunit MAPKAP1; Mitogen-activated protein kinase 2-associated protein 1; TORC2 subunit MAPKAP1; mitogen-activated protein kinase associated protein 1], [MAPKAP1; MAPKAP1; MIP1; SIN1; JC310; SIN1b; SIN1g; MIP1; SIN1; TORC2 subunit MAPKAP1; SAPK-interacting protein 1; mSIN1] |
Gene, Accession # | [MAPKAP1], Gene ID: 79109, NCBI: NP_001006618, UniProt: Q9BPZ7 |
Catalog # | MBS150267 |
Price | $375 |
Order / More Info | MAPKAP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |