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Antigenic Specificity | Human ESTROGEN RECEPTOR ALPHA |
Clone | [6F11] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 1 mL |
Concentration | n/a |
Applications | Immunohistology Frozen*, Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Human estrogen alpha antibody, clone 6F11 recognizes the human estrogen receptor alpha chain (ERalpha), also known as the estradiol receptor or nuclear receptor subfamily 3 group A member 1. ERalpha is a ~65kDa steroid hormone receptor containing an N-terminal AF-1).ligand independent transactivation domain, a DNA binding domain and a C-terminal ligand binding domain which overlaps with an AF-2 domain. ERalpha binds to DNA as a homodimer (Klinge 2001) and can also form heterodimers with Estrogen receptor beta (ERbeta) The detection of estrogen (ER) and progesterone (PR) receptors using immunohistochemical staining of formalin fixed, paraffin embedded (FFPE) tissue, has gradually replaced ligand binding assays, to become the most |
Immunogen | Immunogen: Recombinant human estrogen receptor (alpha form) Histology Positive Control Tissue: Breast carcinoma Fusion Partners: Spleen cells from immunised mice were fused with cells of the mouse p3-NS1-Ag4-1 myeloma cell line Target Species: Human |
Other Names | [estrogen receptor isoform 1; Estrogen receptor; estrogen receptor; ER-alpha; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; nuclear receptor subfamily 3 group A member 1; estrogen receptor 1; ER-alpha; Estradiol receptor; Nuclear receptor subfamily 3 group A member 1], [ESR1; ESR1; ER; ESR; Era; ESRA; ESTRR; NR3A1; ESR; NR3A1; ER] |
Gene, Accession # | Gene ID: 2099, NCBI: NP_000116.2, UniProt: P03372 |
Catalog # | MBS214054 |
Price | $1535 |
Order / More Info | Human ESTROGEN RECEPTOR ALPHA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |