CD137/Tnfrsf9 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD137/Tnfrsf9 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA Capture (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for CD137 detection. Tested with WB, ELISA (Cap) in Mouse; Rat.Background: CD137 is a member of the tumor necrosis factor (TNF) receptor family. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. |
| Immunogen | Immunogen: E Coli-derived mouse CD137 recombinant protein (Position: V24-L187). |
| Other Names | [Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor; T-cell antigen 4-1BB; CD137; Tnfrsf9; Cd137; Ila; Ly63; TNF receptor superfamily member 9] |
| Gene, Accession # | [CD137], Gene ID: 21942, NCBI: NP_001070977.1, UniProt: P20334 |
| Catalog # | MBS1751282 |
| Price | $280 |
| Order / More Info | CD137/Tnfrsf9 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. McNamara, J. O., II, Kolonias, D., Pastor, F., Mittler, R. S., Chen, L., Giangrande, P. H., Sullenger, B., Gilboa, E. Multivalent 4-1BB binding aptamers costimulate CD8 T cells and inhibit tumor growth in mice. J. Clin. Invest. 118: 376-386, 2008. 2. Munks, M. W., Mourich, D. V., Mittler, R. S., Weinberg, A. D., Hill, A. B. 4-1BB and OX40 stimulation enhance CD8 and CD4 T-cell responses to a DNA prime, poxvirus boost vaccine.Immunology 112: 559-566, 2004. 3. Seo, S. K., Choi, J. H., Kim, Y. H., Kang, W. J., Park, H. Y., Suh, J. H., Choi, B. K., Vinay, D. S., Kwon, B. S. 4-1BB-mediated immunotherapy of rheumatoid arthritis. Nature Med. 10: 1088-1094, 2004. Note: Erratum: Nature Med. 10: 1261 only, 2004. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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