Park7 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Park7 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Park7 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | 100ug/100ul |
| Applications | Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human, cow and mouse. |
| Immunogen | Immunogen: DJ-1, also known as Park7, is a cytoplasmic protein that belongs to the ThiJ/Pfp1/DJ1 superfamily that function as protein chaperones, catalases, proteases and kinases. DJ-1 was originally cloned as an oncogene that cooperatively transforms cells together with H-ras (1). Mutations in the DJ-1 gene are associated with rare forms of autosomal recessive early-onset Parkinson's disease (2). DJ-1 may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it app |
| Other Names | n/a |
| Gene, Accession # | [Park7] |
| Catalog # | MBS415245 |
| Price | $370 |
| Order / More Info | Park7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nagakubo D, Taira T, Kitaura H, Ikeda M, Tamai K, Iguchi-Ariga SM and Ariga H DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras. Biochem. Biophys. Res. Commun. 231, 509 -513 (1997).2. Bonifati V, Rizzu P, van Baren, M.J., Schaap O, Breedveld GJ, Krieger E, Dekker MC, Squitieri F, Ibanez P, Joosse M et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset Parkinsonism. Science, 299, 256 -259 (2003).3. Xu J, Zhong N, Wang H, Elias JE, Kim CY, Woldman I, Pifl C, Gygi SP, Geula C, Yankner BA. The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis. Hum Mol Genet. 14 (9):1231-41 (2005)4. Yokota T, Sugawara K, Ito K, Takahashi R, Ariga H. And Mizusawa, H. Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition. Biochem. Biophys. Res. Commun., 312, 1342 -1348 (2003).5. Taira T, Saito Y, Niki T, Iguchi-Ariga SM, Takahashi K and Ariga H. DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep., 5, 213 -218 (2004).6. Bonifati V, Oostra BA. and Heutink, P. Linking DJ-1 to neurodegeneration offers novel insights for understanding the pathogenesis of Parkinsona's disease. J.Mol,Med.82,163-174 (2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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