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Antigenic Specificity | Human CD58 |
Clone | [MEM-63] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 100 tests |
Concentration | IgG concentration 0.1 mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD58, or LFA-3, is a membrane glycoprotein of 55-70kD. It occurs in two forms, one transmembrane with a cytoplasmic domain, the other form anchored in the membrane via a glycosylphosphatidylinositol tail. The complete amino acid sequence of both forms has been deduced from cDNA. It is heavily N-glycosylated. CD58 is a cell adhesion molecule which plays a critical role in facilitation of antigen specific recognition through interaction with CD2 on T lymphocytes[1]. It is a member of the immunoglobulin superfamily of molecules.CD58 has a wide tissue distribution, being present on erythrocytes, platelets, monocytes, a subset of lymphocytes, bone marrow cells, epithelium and endothelial cells[2]. There are approximately 5,000 CD58 |
Immunogen | n/a |
Other Names | [lymphocyte function-associated antigen 3 isoform 2; Lymphocyte function-associated antigen 3; lymphocyte function-associated antigen 3; CD58 antigen, (lymphocyte function-associated antigen 3); surface glycoprotein LFA-3; CD58 molecule; Surface glycoprotein LFA-3; CD_antigen: CD58], [CD58; CD58; ag3; LFA3; LFA-3; LFA3; Ag3] |
Gene, Accession # | [CD58], Gene ID: 965, NCBI: NP_001138294.1 |
Catalog # | MBS210848 |
Price | $370 |
Order / More Info | Human CD58 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |