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Antigenic Specificity | EXOSC4 (Center), 69-96 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This EXOSC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-96 amino acids from the Central region of human EXOSC4. Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. Required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease activity. Plays a role in replication-dependent histone mRNA degradation. |
Immunogen | n/a |
Other Names | [Exosome complex component RRP41; Exosome component 4; Ribosomal RNA-processing protein 41; p12A; EXOSC4; RRP41; SKI6] |
Gene, Accession # | [EXOSC4], Gene ID: 54512, NCBI: NP_061910.1, UniProt: Q9NPD3 |
Catalog # | MBS9202120 |
Price | $165, $370 |
Order / More Info | EXOSC4 (Center), 69-96 Antibody from MYBIOSOURCE INC. |
Product Specific References | Mullen, T.E., et al. Genes Dev. 22(1):50-65(2008) van Dijk, E.L., et al. RNA 13(7):1027-1035(2007) Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005) Andersen, J.S., et al. Nature 433(7021):77-83(2005) Lehner, B., et al. Genome Res. 14(7):1315-1323(2004) |