TRICK2 (DR5, TRAIL-R2) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TRICK2 (DR5, TRAIL-R2) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunoblot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TRICK2 (DR5,TRAIL-R2) [Human TRICK2 (DR5, TRAIL-R2)]. This antibody recognizes human TRICK2. Apoptosis is induced by cytokines in the TNF family through their death domain containing receptors. TRICK2 (TRAIL receptor inducer of cell killing 2) is a member of the TNF receptor family and contains the conserved death domain. TRICK2 is expressed at high levels in lymphocytes and spleen cells and in many types of tumor cells. Overexpression of TRICK2 rapidly induces cell death by apoptosis. TRICK2 has been shown to function as a receptor for TRAIL and can inhibit TRAIL-induced killing of lymphocytic cells. Other names for TRICK2 include DR5, Apo2, TRAIL-R2, and KILLER. |
| Immunogen | Immunogen: Synthetic peptide corresponding to amino acids 409-427 (LGERLAKQKIEDHLLSSGK, isoform 1) of human TRICK2 precursor conjugated to KLH at the N-terminus. The same sequence is found at amino acids 380-398 in isoform 2. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS194148 |
| Price | $335 |
| Order / More Info | TRICK2 (DR5, TRAIL-R2) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Screaton,GR et al. (1997) Curr Biol 7: 693-696. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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