Human NOXA Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human NOXA |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 0.5mg/ml |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item specifically recognises human Noxa, a mitochondrial localised protein and member of the BH3-only proapoptotic protein family, which is up-regulated by p53, IFNbeta, phorbol esters, dsRNA and viruses, and acts as promoter of caspase and apoptosis activation.. . Noxa is a transcriptional target of p53, p73 and BH3-only proteins, and competes with, and displaces, the proapoptotic proteins BAK1, and BIM, from the antiapoptotioc protein MCL1 (Bcl-2-related protein EAT/mcl1), thereby influencing apoptosis versus cell survival. MBS224213 specifically recognises human Noxa, a mitochondrial localised protein and member of the BH3-only proapoptotic protein family, which is up-regulated by p53, IFNbeta, phorbol esters, dsRNA and viruses, a |
| Immunogen | Immunogen: Synthetic peptide sequence C-TQLRRFGDKLNFRQK from the internal region of Noxa (NP 066950.1). Buffer Solution: TRIS buffered saline Antiserum Preparation: Antiserum to human NOXA was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Human |
| Other Names | [phorbol-12-myristate-13-acetate-induced protein 1; Phorbol-12-myristate-13-acetate-induced protein 1; phorbol-12-myristate-13-acetate-induced protein 1; PMA-induced protein 1; adult T cell leukemia-derived PMA-responsive; immediate-early-response protein APR; protein Noxa; phorbol-12-myristate-13-acetate-induced protein 1; Immediate-early-response protein APR; Protein Noxa], [PMAIP1; PMAIP1; APR; NOXA; NOXA; PMA-induced protein 1] |
| Gene, Accession # | [NOXA], Gene ID: 5366, NCBI: NP_066950.1, UniProt: Q13794 |
| Catalog # | MBS224213 |
| Price | $550 |
| Order / More Info | Human NOXA Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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