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Antigenic Specificity | ERCC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ERCC1 protein. Isoform 1:Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.Kan-Tai Hsia, Development, Jan 2003; 130: 369.Jim Selfridge, Nucleic Acids Res., Nov 2001; 29: 4541 - 4550.Cha-Kyung Youn, Cancer Res., Jul 2004; 6 |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human ERCC1. |
Other Names | [UV20; DNA REPAIR DEFECT UV-20 OF CHINESE HAMSTER OVARY CELLS; COMPLEMENTATION OF EXCISION-REPAIR; COMPLEMENTING DEFECTIVE IN CHINESE HAMSTER; excision repair cross-complementing 1 isoform 1] |
Gene, Accession # | [ERCC1], Gene ID: 2067, NCBI: NP_001159521.1, UniProt: P07992 |
Catalog # | MBS9412109 |
Price | $200, $255 |
Order / More Info | ERCC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |