ERCC1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityERCC1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total ERCC1 protein. Isoform 1:Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.Kan-Tai Hsia, Development, Jan 2003; 130: 369.Jim Selfridge, Nucleic Acids Res., Nov 2001; 29: 4541 - 4550.Cha-Kyung Youn, Cancer Res., Jul 2004; 6
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human ERCC1.
Other Names[UV20; DNA REPAIR DEFECT UV-20 OF CHINESE HAMSTER OVARY CELLS; COMPLEMENTATION OF EXCISION-REPAIR; COMPLEMENTING DEFECTIVE IN CHINESE HAMSTER; excision repair cross-complementing 1 isoform 1]
Gene, Accession #[ERCC1], Gene ID: 2067, NCBI: NP_001159521.1, UniProt: P07992
Catalog #MBS9412109
Price$200, $255
Order / More InfoERCC1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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