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Antigenic Specificity | Phospho-RPS6KA5 (S376) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes (PubMed:11909979, PubMed:12569367, PubMed:12763138, PubMed:9687510, PubMed:18511904, PubMed:9873047). Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin (PubMed:11909979, PubMed:9873047). Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-RPS6KA5 (S376) |
Other Names | [Ribosomal protein S6 kinase alpha-5; S6K-alpha-5; 90 kDa ribosomal protein S6 kinase 5; Nuclear mitogen-and stress-activated protein kinase 1; RSK-like protein kinase; RSKL; RPS6KA5; MSK1] |
Gene, Accession # | [RPS6KA5], Gene ID: 9252, NCBI: NP_001309164.1, UniProt: O75582 |
Catalog # | MBS7114898 |
Price | $185, $265 |
Order / More Info | Phospho-RPS6KA5 (S376) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |