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Antigenic Specificity | Mouse CD90.2 |
Clone | [30H12] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature |
Immunogen | n/a |
Other Names | [Mouse CD90.2; Thy-1.2 membrane glycoprotein; Thy1.2; Thy-1.2 antigen; CD90.2; Thy-1.2] |
Gene, Accession # | [CD90.2], Gene ID: 21838, NCBI: NP_033408.1, UniProt: P01831 |
Catalog # | MBS2553899 |
Price | $90, $110 |
Order / More Info | Mouse CD90.2 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Craig W, et al. 1993. J. Exp. Med. 177:1331. 3. Reif AE and Schlesinger M. 1989. Cell Surface Antigen Thy-1. 4. Mayani H, et al. 1994. Blood 83:2410. |