TRPM7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRPM7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: TRPM7 antibody detects endogenous levels of total TRPM7. Function: Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1).Subunit Structure: Homodimer. Interacts with PLCB1 (By similarity). Forms heterodimers with TRPM6.Post-translational Modificat
ImmunogenImmunogen: A synthesized peptide derived from human TRPM7 Subcellular Location: Membrane. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (91%), Horse (82%), Sheep (91%), Rabbit (100%), Dog (91%)
Other Names[ALSPDC; CHAK; CHAK1; Channel kinase 1; Channel-kinase 1; Long transient receptor potential channel 7; LTrpC-7; LTrpC7; Transient receptor potential cation channel subfamily M member 7; TRP PLIK; TRPM7; TRPM7_HUMAN]
Gene, Accession #[TRPM7], Gene ID: 54822, NCBI: NP_001288141.1, UniProt: Q96QT4
Catalog #MBS9608695
Price$240, $280
Order / More InfoTRPM7 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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