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Antigenic Specificity | MALT1 |
Clone | [4D3F6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 belongs to caspase-like protein superfamily.MALT1 plays a potential role in the regulation of apoptosis and induces NFKB activation and required for the normal development of B cells and for the activation of the IKK complex.It acts as a caspase and mediates additional functions related to T cell activation, cleaving both the ubiquitin editing enzyme, TNFAIP3, and the C terminus of BCL10.It has two isoforms.Researches showed that inhibition of MALT1 blocks A20 and BCL10 cleavage, reduces NFKB activity, and decreases the expression of NFKB targets BCLXL. |
Immunogen | Immunogen: Fusion Protein of MALT1 Buffer: PBS with 0.02% sodium azide, 50% glycerol, PH7.3 Conjugation: Unconjugated |
Other Names | [DKFZp434L132; MALT1; MLT; MLT1; Paracaspase] |
Gene, Accession # | [MALT1], Gene ID: 10892, NCBI: BC030143, UniProt: Q9UDY8 |
Catalog # | MBS2549095 |
Price | $220, $290, $435 |
Order / More Info | MALT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |