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Antigenic Specificity | AGT (N-term), 37-65 |
Clone | [656CT5.8.4] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This AGT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human AGT. The protein encoded by this gene, pre-angiotensinogen orangiotensinogen precursor, is expressed in the liver and is cleavedby the enzyme renin in response to lowered blood pressure. Theresulting product, angiotensin I, is then cleaved by angiotensinconverting enzyme (ACE) to generate the physiologically activeenzyme angiotensin II. The protein is involved in maintaining bloodpressure and in the pathogenesis of essential hypertension andpreeclampsia. Mutations in this gene are associated withsusceptibility to essential hypertension, and can cause renal |
Immunogen | n/a |
Other Names | [Angiotensinogen; Serpin A8; Angiotensin-1; Angiotensin 1-10; Angiotensin I; Ang I; Angiotensin-2; Angiotensin 1-8; Angiotensin II; Ang II; Angiotensin-3; Angiotensin 2-8; Angiotensin III; Ang III; Des-Asp[1]-angiotensin II; Angiotensin-4; Angiotensin 3-8; Angiotensin IV; Ang IV; Angiotensin 1-9; Angiotensin 1-7; Angiotensin 1-5; Angiotensin 1-4; AGT; SERPINA8] |
Gene, Accession # | [AGT], Gene ID: 183, NCBI: NP_000020.1, UniProt: P01019 |
Catalog # | MBS9200414 |
Price | $370 |
Order / More Info | AGT (N-term), 37-65 Antibody from MYBIOSOURCE INC. |
Product Specific References | Desong, Liu., et al. J Renin Angiotensin Aldosterone Syst 11(4):248-255(2010) Procopciuc, L.M., et al. Eur. J. Intern. Med. 21(5):414-418(2010) Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) : Hajjar, I., et al. J Am Geriatr Soc 58(6):1035-1042(2010) Kiec-Wilk, B., et al. Prz. Lek. 67(3):151-156(2010) |