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Antigenic Specificity | SPAK (Center), 346-376 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This SPAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-376 amino acids from the Central region of human SPAK. SPAK is a serine/threonine kinase containing an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain, a nuclear localization signal, a consensus caspase cleavage recognition motif, and a C-terminal region. Northern blot analysis detects ubiquitous expression, most abundantly in brain and pancreas.SPAK can phosphorylate itself and an exogenous substrate in vitro. SPAK immunoprecipitates from transfected mammalian cells in a complex with another serine/threonine kinase that phosphorylates catalytically inactive SP |
Immunogen | n/a |
Other Names | [STE20/SPS1-related proline-alanine-rich protein kinase; Ste-20-related kinase; DCHT; Serine/threonine-protein kinase 39; STK39; SPAK] |
Gene, Accession # | [STK39], Gene ID: 27347, NCBI: NP_037365.2, UniProt: Q9UEW8 |
Catalog # | MBS9210930 |
Price | $165, $370 |
Order / More Info | SPAK (Center), 346-376 Antibody from MYBIOSOURCE INC. |
Product Specific References | Dowd, B.F., et al., J. Biol. Chem. 278(30):27347-27353 (2003). Johnston, A.M., et al., Oncogene 19(37):4290-4297 (2000). |