SPAK (Center), 346-376 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySPAK (Center), 346-376
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse (predicted reactivity: rat)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis SPAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-376 amino acids from the Central region of human SPAK. SPAK is a serine/threonine kinase containing an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain, a nuclear localization signal, a consensus caspase cleavage recognition motif, and a C-terminal region. Northern blot analysis detects ubiquitous expression, most abundantly in brain and pancreas.SPAK can phosphorylate itself and an exogenous substrate in vitro. SPAK immunoprecipitates from transfected mammalian cells in a complex with another serine/threonine kinase that phosphorylates catalytically inactive SP
Immunogenn/a
Other Names[STE20/SPS1-related proline-alanine-rich protein kinase; Ste-20-related kinase; DCHT; Serine/threonine-protein kinase 39; STK39; SPAK]
Gene, Accession #[STK39], Gene ID: 27347, NCBI: NP_037365.2, UniProt: Q9UEW8
Catalog #MBS9210930
Price$165, $370
Order / More InfoSPAK (Center), 346-376 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesDowd, B.F., et al., J. Biol. Chem. 278(30):27347-27353 (2003). Johnston, A.M., et al., Oncogene 19(37):4290-4297 (2000).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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