LEPR Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityLEPR
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunofluorescence (IF)
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DescriptionReceptor for hormone LEP/leptin (Probable) (PubMed: 22405007). On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones (By similarity) (PubMed: 9537324). In the periphery, increases basal metabolism, influences reproductive function, regulates pancreatic beta-cell function and insulin secretion, is pro-angiogenic and affects innate and adaptive im
ImmunogenImmunogen: Recombinant Human Leptin receptor protein (874-1075AA)
Other Names[Leptin receptorLEP-R; HuB219; OB receptor; OB-R; CD295; LEPR; DB; OBR]
Gene, Accession #[LEPR], Gene ID: 3953, NCBI: NP_001003679.1, UniProt: P48357
Catalog #MBS7049480
Price$160, $235
Order / More InfoLEPR Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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